The story takes place largely on Roanoke Island, which is governed by Ananias Dare. His daughter Virginia and Peter Parquagh (this world's Spider-Man) are fighting an invasion of dinosaurs, and tensions between the colonists and Native Americans are increasing, with Englishman Norman Osborne attempting to cheat the natives out of the island. Unrest about metahumans is also increasing, led by newspaperman J. Jonah Jameson. Osbourne is quick to blame this on the natives and Rojhaz (this world's Captain America).